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VOLUME 14 , ISSUE 3 ( June, 2021 ) > List of Articles

¿Siempre se Tiene que Extraer la Membrana Limitante Interna (MLI) en los Procedimientos Quirúrgicos de Ciertas Afecciones Retinales? ¿Por Qué Si/No?

Dr. Juan Manuel Cortalezzi, Dr. Juan Pablo Francos, Dr. Alejandro Alfano, Dr. Ignacio Olmedo, Dr. Mariano Cotic, Dr. Marcos Mendaro, Prof. Dr. Marcelo Zas

Keywords : Revisión de literatura, sistemática, membrana limitante interna (MLI), cirugía retinal, pucker macular, agujero macular, retinosquisis, desprendimiento de retina, edema macular diabético

Citation Information : Cortalezzi DJ, Francos DJ, Alfano DA, Olmedo DI, Cotic DM, Mendaro DM, Zas PD. ¿Siempre se Tiene que Extraer la Membrana Limitante Interna (MLI) en los Procedimientos Quirúrgicos de Ciertas Afecciones Retinales? ¿Por Qué Si/No?. 2021; 14 (3):21-33.

DOI: 10.5005/hov-10102-14303

Published Online: 10-12-2021

Copyright Statement:  Copyright © 2021; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Objetivo: Es nuestro objetivo clarificar la indicación o no de la extracción quirúrgica de la Membrana Limitante Interna (MLI) según revisión bibliográfica en diferentes patologías retínales. Antecedentes: No está claro si este paso, el peeling de la MLI es crítico, conveniente o importante en la resolución de diferentes patologías retinales. Como tampoco su beneficio en el resultado visual final. Conclusión: Según nuestro review bibliográfico no es en todas las patologías mencionadas recomendable o determinante su realización, en lograr un buen resultado tanto visual como anatómico. La afección en la cual es más clara su indicación es la del agujero macular. Importancia Clínica: Analizamos la utilidad del procedimiento quirúrgico en ciertas afecciones maculares como en el agujero macular y otras. No sería indicativo su realización en el pucker macular por default. En el edema macular diabético, desprendimiento de retina y retinosquisis, los resultados no son concluyentes.

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  1. Morris R, Kuhn F, Witherspoon CD. Hemorrhagic macular cysts. Ophthalmology 1994;101:1.
  2. Park DW, Dugel PU, Garda J, et al. Macular pucker removal with and without internal limiting membrane peeling: pilot study. Ophthalmology 2003;110:62–64.
  3. Lois N, Burr J, Norrie J, et al. Internal limiting membrane peeling versus no peeling for idiopathic full-thickness macular hole: a pragmatic randomized controlled trial. Invest Ophthalmol Vis Sci. 2011;52:1586 –1592.
  4. Spiteri Cornish K, Lois N, Scott NW, et al. Vitrectomy with internal limiting membrane peeling versus no peeling for idiopathic full-thickness macular hole. Ophthalmology. 2014;121(3):649-655.
  5. Evaluating inner retinal dimples after inner limiting membrane removal using multimodal imaging of optical coherence tomography. Jingjing Liu, Yiye Chen, Shiyuan Wang, Xiang Zhang and Peiquan Zhao. BMC Ophthalmology (2018) 18:155.
  6. Tadayoni R, Paques M, Massin P, et al. Dissociated optic nerve fiber layer appearance of the fundus after idiopathic epiretinal membrane removal. Ophthalmology. 2001;108:2279–2283.
  7. Terasaki H, Miyake Y, Nomura R, et al. Focal macular ERGs in eyes after removal of macular ILM during macular hole surgery. Invest Ophthalmol Vis Sci 2001;42:229–234.
  8. Grewing R, Mester U. Results of surgery for epiretinal membranes and their recurrences. Br J Ophthalmol 1996; 80:323–326.
  9. Holländer H, Makarov F, Dreher Z, et al. Structure of the macroglia of the retina: sharing and division of labour between astrocytes and Müller cells. J Comp Neurol 1991;313:587–603.
  10. Sebag J. Age-related differences in the human vitreoretinal interface. Arch Ophthalmol 1991;109:966–71.
  11. Ripandelli G, Scarinci F, Piaggi P, et al. Macular pucker: to peel or not to peel the internal limiting membrane? A microperimetric response. Retina 2015;35:498–507.
  12. Nitta E, Shiraga F, Shiragami C, et al. Displacement of the retina and its recovery after vitrectomy in idiopathic epiretinal membrane. Am J Ophthalmol 2013;155:1014–1020.e1.
  13. Haritoglou C, Schumann R, Reiniger I, et al. Evaluation of the internal limiting membrane after conventional peeling during macular hole surgery. Retina 2006;26:21–4.
  14. Sandali O, El Sanharawi M, Basli E, et al. Paracentral retinal holes occurring after macular surgery: incidence, clinical features, and evolution. Graefes Arch Clin Exp Ophthalmol 2012; 250:1137–1142.
  15. Rush RB, Simunovic MP, Aragon AV II, Ysasaga JE. Post-operative macular hole formation after vitrectomy with internal limiting membrane peeling for the treatment of epiretinal mem- brane. Retina 2014;34:890–896.
  16. Dysli M, Ebneter A, Menke MN, et al. Patients with epiretinal membranes display retrograde maculopathy after surgical peeling of the internal limiting membrane. Retina. 2019;39(11):2132-2140.
  17. Kerrigan-Baumrind LA, Quigley HA, Pease ME, Kerrigan DF, Mitchell RS. Number of ganglion cells in glaucoma eyes compared with threshold visual field tests in the same persons. Invest Ophthalmol Vis Sci. 2000;41(3):741–8.
  18. Harwerth RS, Carter-Dawson L, Smith EL 3rd, Barnes G, Holt WF, Crawford ML. Neural losses correlated with visual losses in clinical perimetry. Invest Ophthalmol Vis Sci. 2004;45(9):3152–60.
  19. De Novelli FJ, Goldbaum M, Monteiro MLR, Bom Aggio F, Takahashi WY. Surgical removal of epiretinal membrane with and without removal of internal limiting membrane: Comparative Study of Visual Acuity, Features of Optical Coherence Tomography, and Recurrence Rate. Retina. 2019;39(3):601-607.
  20. Donati G, Kapetanios AD, Pournaras CJ. Complications of surgery for epiretinal membranes. Graefes Arch Clin Exp Ophthalmol 1998; 236:739–746.
  21. Roh M, Eliott D. Internal limiting membrane peeling during idiopathic epiretinal membrane removal: literature review. Int Ophthalmol Clin 2015;55:91–101.
  22. Díaz-Valverde A, Wu L. To peel or not to peel the internal limiting membrane in idiopathic epiretinal membranes. Retina. 2018;38 Suppl 1:S5-S11.
  23. Schechet SA, DeVience E, Thompson JT. The effect of internal limiting membrane peeling on idiopathic epiretinal membrane surgery, with a review of the literature. Retina. 2017;37(5):873-880.
  24. H. Lewis, G. W. Abrams, M. S. Blumenkranz, and R. V. Campo, “ Vitrectomy for diabetic macular traction and edema associated with posterior hyaloidal traction ” Ophthalmology, vol. 99, no. 5, pp. 753–759, 1992.
  25. Gandorfer A, Messmer EM, Ulbig MW et al (2000) Resolution of diabetic macular edema after surgical removal of the posterior hyaloid and the inner limiting membrane. Retina 20(2):126– 133.
  26. Harbour JW, Smiddy WE, Flynn HW et al (1996) Vitrectomy for diabetic macular edema associated with a thickened and taut posterior hyaloid membrane. Am J Ophthalmol 121(4):405–413.
  27. Nakajima T, Roggia MF, Noda Y, Ueta T. Effect of internal limiting membrane peeling during vitrectomy for diabetic macular edema: Systematic Review and Meta-analysis. Retina. 2015;35(9):1719-1725.
  28. Rinaldi M, dell'Omo R, Morescalchi F, et al. ILM peeling in nontractional diabetic macular edema: review and metanalysis. Int Ophthalmol. 2018;38(6):2709-2714.
  29. Gandorfer A, Kampik A. Pars plana vitrectomy with and without peeling of the inner limiting membrane (ILM) for diabetic macular edema. Retina. 2008;28(1):187-189.
  30. Rosenblatt BJ, Shah GK, Sharma S, Bakal J (2005) Pars plana vitrectomy with internal limiting membra- nectomy for refractory diabetic macular edema without a taut posterior hyaloid. Graefes Arch Clin Exp Ophthalmol 243: 20–25.
  31. Fallico M, Russo A, Longo A, et al. Internal limiting membrane peeling versus no peeling during primary vitrectomy for rhegmatogenous retinal detachment: A systematic review and meta-analysis. PLoS One. 2018;13(7):e0201010. Published 2018 Jul 19.
  32. Akiyama K, Fujinami K, Watanabe K, Tsunoda K, Noda T. Internal Limiting Membrane Peeling to Prevent Post-vitrectomy Epiretinal Membrane Development in Retinal Detachment. Am J Ophthalmol. 2016;171:1-10. doi:10.1016/j.ajo.2016.08.015
  33. Kumar V, Dubey D, Kumawat D, et al. Role of internal limiting membrane peeling in the prevention of epiretinal membrane formation following vitrectomy for retinal detachment: a randomised trial [published online ahead of print, 2019 Dec 16]. Br J Ophthalmol. 2019;bjophthalmol-2019-315095.
  34. Forlini M, Date P, Ferrari LM, Lorusso M, Lecce G, Verdina T, Neri G, Benatti C, Rossini P, Bratu A, D'Eliseo D, Ferrari TM, Cavallini GM. Comparative analysis of retinal reattachment surgery with or without internal limiting membrane peeling to prevent postoperative macular pucker. Retina. 2018 Sep;38(9):1770-1776.
  35. Spaide RF. “Dissociated optic nerve fiber layer appearance” after internal limiting membrane removal is inner retinal dimpling. Retina 2012; 32:1719–26.
  36. Fukukita H, Ito Y, Iwase T, et al. Inner macular changes after vitrectomy with internal limiting membrane peeling for rhegmatogenous retinal detachment: Similarity With Alport Syndrome. Retina. 2019;39(12):2332-2340.
  37. Peng KL, Kung YH, Hsu CM, Chang SP, Tseng PL, Wu TT. Surgical outcomes of centripetal non-fovea-sparing internal limiting membrane peeling for myopic foveoschisis with and without foveal detachment: a follow-up of at least 3 years [published online ahead of print, 2019 Dec 12]. Br J Ophthalmol. 2019; bjophthalmol-2019-314972.
  38. Ho T-C, Yang C-M, Huang J-S, et al. Long-Term outcome of foveolar internal limiting membrane nonpeeling for myopic traction maculopathy. Retina 2014;34:1833–40.
  39. Lee C-L, Wu W-C, Chen K-J, et al. Modified internal limiting membrane peeling technique (maculorrhexis) for myopic foveoschisis surgery. Acta Ophthalmol 2017;95:e128–31.
  40. Gui J, Ai L, Huang T. Vitrectomy with or without internal limiting membrane peeling for myopic foveoschisis. BMC Ophthalmol. 2020;20(1):83. Published 2020 Mar 4.
  41. Tian T, Jin H, Zhang Q, Zhang X, Zhang H, Zhao P. Long-term surgical outcomes of multiple parfoveolar curvilinear internal limiting membrane peeling for myopic foveoschisis. Eye (Lond). 2018 Nov;32(11):1783-1789.
  42. Shinohara K, Shimada N, Takase H, Ohno-Matsui K. Functional and structural outcomes after fovea-sparing internal limiting membrane peeling for myopic macular retinoschisis by microperimetry [published online ahead of print, 2019 Jul 30]. Retina. 2019;10.
  43. Stefánsson E. Ocular oxygenation and the treatment of diabetic retinopathy. Surv Ophthalmol 2006;51:364–380.
  44. Kadonosono K, Itoh N, Ohno S. Perifoveal microcirculation before and after vitrectomy for diabetic cystoid macular edema. Am J Ophthalmol 2000;130:740–744.
  45. Christoforidis JB, D'Amico DJ. Surgical and other treatments of diabetic macular edema: an update. Int Ophthalmol Clin 2004;44:139–160.
  46. Yamada Y, Suzuma K, Kumagami T, Fujikawa A, Kitaoka T. Systemic factors influence the prognosis of diabetic macular edema after pars plana vitrectomy with internal limiting membrane peeling. Ophthalmologica. 2013;229(3):142-6.
  47. Hu XY, Liu H, Wang LN, Ding YZ, Luan J. Efficacy and safety of vitrectomy with internal limiting membrane peeling for diabetic macular edema: a Meta-analysis. Int J Ophthalmol 2018;11(11):1848-1855.
  48. Iglicki M, Loewenstein A, Barak A, Schwartz S, Zur D (2020) Outer retinal hyperreflective deposits (ORYD): a new OCT feature in naïve diabetic macular oedema after PPV with ILM peeling. Br J Ophthalmol 104: 666–671.
  49. Alkabes M, Salinas C, Vitale L, Burés-Jelstrup A, Nucci P, Mateo C. En face optical coherence tomography of inner retinal defects after internal limiting membrane peeling for idiopathic macular hole. Invest Ophthalmol Vis Sci. 2011;52(11):8349-8355. Published 2011 Oct 21.
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